Deca Durabolin (nandrolone decanoate)

Deca Durabolin is the injectable steroid

Deca Durabolin is the Organon brand name for the injectable steroid nandrolone decanoate. It came around early in the wave of commercial steroid development, first being made available as a prescription medication in 1962. This steroid is an extremely long acting compound, with the decanoate ester said to provide it a slow release time of up to three or four weeks. While perhaps true in a technical sense, what we find with further investigation is that the release parameters after a single injection are such that a strong release of Deca Durabolin is really only maintained for one to two weeks. This figure admittedly fails to take into account drug buildup that may occur after multiple injections, which may allow a longer duration of good effect to be seen.

Deca Durabolin side effects

World Wide Deca Durabolin is one of the most widely used anabolic steroids. It popularity is due to the simple fact that it exhibits many very favorable properties. Structurally Deca Durabolin is very similar to testosterone, although it lacks a carbon atom at the 19t" position (hence its other name 19-nortestosterone). The resulting structure is a steroid that exhibits much weaker androgenic properties than testosterone. Of primary interest is the fact that this drug will not break down to a more potent metabolite in androgen target tissuess. You may remember this is a significant problem with testosterone. Although Deca Durabolin does undergo reduction via the same (5-alpha reductase) enzyme that produces DHT from testosterone, the result in this case is dihydronandrolone. This metabolite is weaker than the parent nandroloness, and is far less likely to cause unwanted androgenic side effects. Strong occurrences of oily skin, acne, body/facial hair growth and hair loss occur very rarely. It is however possible for androgenic activity to become apparent with this as any steroid, but higher than normal doses are usually responsible.

Deca Durabolin and estrogen conversion

Deca Durabolin also show an extremely lower tendency for estrogen conversion. For comparison, the rate has been estimated to be only about 20% of that seen with testosterones. This is because while the liver can convert nandrolone to estradiol, in other more active sites of steroid aromatization such as adipose tissue nandrolone in is far less open to this process. Consequently estrogen related side effects are a much lower concern with Deca Durabolin. An antiestrogen is likewise rarely needed with Deca, gynecomastia only a worry among sensitive individuals. At the same time water retention is not a usual concern. This effect can occur however, but is most often related to higher dosages. The addition of Proviron and/or Nolvadex should prove sufficient enough to significantly reduce any occurrence. Clearly Deca Durabolin is a very safe choice among steroids. Actually, many consider the steroid to be the best overall steroid for a man to use when weighing the side effects and results. It should also be noted that in HIV studies, Deca Duraboin has been shown not only to be effective at safely bringing up the lean body weight of patient, but also to be beneficial to the immune system.

Nandrolone in Deca Durabolin

It is of note however that nandrolone is believed to have some activity as a progestin in the body". Although progesterone is a c-19 steroid, removal of this group as in 19-norprogesterone creates a hormone with greater binding affinity for its corresponding receptor. Sharing this trait, many 19-nor anabolic steroids are shown to have some affinity for the progesterone receptor as well'2. This can lead to some progestin-like activity in the body, and may intensify related side effects. The side effects of Deca Durabolin associated with progesterone are actually quite similar to those of estrogen, including negative feedback inhibition of testosterone production, enhanced rate of fat storage and possibly gynecomastia. Many believe the progestin activity of Deca Durabolin notably contributes to suppression of testosterone synthesis, which can be marked despite a low tendency for estrogen conversion.